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2021-2022 Academic Bulletin (July 2021 Ed) [ARCHIVED CATALOG]
College of Graduate Health Sciences
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920 Madison Avenue, Suite 407 • Memphis, TN 38163 • Phone: (901) 448-5538
Website: www.uthsc.edu/grad/
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Donald B. Thomason, PhD
Dean
Isaac O. Donkor, PhD
Associate Dean, Student Affairs
John V. Cox, PhD
Associate Dean, Academic Affairs
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Monica Jablonski, PhD
Associate Dean, Postdoctoral Affairs
Larry Tague
Assistant Dean, Academic Affairs
Felicia Washington, MHSA
Assistant Dean, Graduate Programs and Services
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Information About the College
Programs
- Biomedical Engineering, MS
- Biomedical Sciences, Laboratory Research and Management Concentration, MS
- Dental Science, MDS
- Epidemiology, Biostatistics Concentration, MS
- Epidemiology, Clinical Investigation Concentration, MS
- Epidemiology, Data Science Concentration, MS
- Pharmacology, MS
- Biomedical Engineering, PhD
- Biomedical Sciences, Cancer and Developmental Biology Concentration, PhD
- Biomedical Sciences, Genetics, Genomics and Informatics Concentration, PhD
- Biomedical Sciences, Microbiology, Immunology, and Biochemistry Concentration, PhD
- Biomedical Sciences, Pharmacology, Addiction Science, and Toxicology Concentration, PhD
- Biomedical Sciences, Neuroscience Concentration, PhD
- Biomedical Sciences, Rehabilitation Sciences Concentration, PhD
- Biomedical Sciences, MS (Transition from PhD)
- Health Outcomes and Policy Research, Health Informatics and Information Management Concentration, PhD
- Health Outcomes and Policy Research, Health Policy/Health Services Research Concentration, PhD
- Health Outcomes and Policy Research, Pharmacoeconomics Concentration, PhD
- Health Outcomes and Policy Research, MS
- Nursing Science, PhD
- Pharmaceutical Sciences, PhD
- Pharmaceutical Sciences, MS (Transition from PhD)
- Speech and Hearing Science, Ph.D.
- Clinical Investigation, Certificate
- Healthcare Quality Improvement, Certificate
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Anatomy and Neurobiology
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ANAT 622 - Head and Neck Anatomy
Cr Hrs: 3 (16-64-0)
GR
A Lecture and Lab study of the gross structures of the head and neck, designed primarily for postdoctoral dental students.
Grade Mode: Standard
Instructional Method: Lecture, Lab
Prerequisites: Permission of instructor
Term offered: Spring
Spring - Instructor of Record: Randall J Nelson
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ANAT 821 - Neuroscience Seminar
Cr Hrs: 1 (16-0-0)
GR
Graduate students and postdoctoral fellows are exposed to the latest concepts, techniques, and developments in basic and clinical neuroscience. Weekly seminars are presented by participating students, postdoctoral fellows, University of Tennessee Health Science Center Faculty, and prominent outside speakers each year.
Repeatability (The maximum credit hours a student may have for this course.): 6
Grade Mode: Standard
Instructional Method: Lecture
Term offered: Fall, Spring
Fall - Instructor of Record: Joseph C Callaway
Spring - Instructor of Record: Joseph C Callaway
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ANAT 823 - Cellular Neuroscience
Cr Hrs: 3 (48-0-0)
GR
This course provides the student with an overview of the cellular and molecular processes by which nerve cells communicate The course covers classical theories and concepts as a basis for appreciation of recent research advances Lectures by the Faculty will provide core material to guide students in presentation of current research topics in Neurochemistry, Neuropharmacology, and Neurophysiology Extensive reading of the literature will supplement lectures and presentations
Grade Mode: Standard
Instructional Method: Lecture
Term offered: Spring
Spring - Instructor of Record: Robert C Foehring
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ANAT 825 - Developmental and Molecular Neurobiology
Cr Hrs: 3 (48-0-0)
GR
This one-term course will serve as an introduction to developmental neurobiology with special emphasis on the molecular analysis of nervous system development. A brief introduction to molecular analysis will be followed by lectures and student- led discussions of research papers that focus on major epochs/events in the development of the nervous system.
Grade Mode: Standard
Instructional Method: Lecture
Prerequisites: Permission of instructor
Term offered: Spring (every other year, even years)
Spring - Instructor of Record: Kristin Marie Hamre
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ANAT 826 - Neuroscience Student Symposia
Cr Hrs: 1 (16-0-0)
GR
Students make scientific presentations, and participate in the discussion of presentations by other students. Presentations are to be based on the students’ own research or on research closely related to their own interests. The presentations are to be given in the style of a scientific meeting, with time allotted for individual talks and discussion.
Repeatability (The maximum credit hours a student may have for this course.): 6
Grade Mode: Standard
Instructional Method: Lecture
Term offered: Spring
Spring - Instructor of Record: Max Fletcher
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ANAT 827 - Functional Neuroanatomy
Cr Hrs: 3 (32-32-0)
GR
A lecture and Lab dealing with the structure and function of the mammalian central nervous system. The emphasis of the course is on human neuroanatomy, but comparisons are made with the rodent brain using the rat and mouse as model systems. The first one-third of the course provides a synopsis of core concepts and tools used in contemporary neuroanatomical research. This material focuses on an understanding of the principles underlying neuroanatomical approaches, as well as their advantages and potential pitfalls. The final two-thirds of the course covers the basic organization of the central nervous system, including in-depth consideration of its major sensory, motor, and limbic components. This part of the course includes laboratory study on the gross anatomy of the brain. An introductory course in neuroscience is highly recommended.
Grade Mode: Standard
Instructional Method: Lecture, Lab
Term offered: Fall, Spring
Fall - Instructor of Record: Matthew Ennis
Spring - Instructor of Record: Joseph C Callaway
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ANAT 840 - Special Topics
Cr Hrs: 1-5
GR
Directed readings or special course in topics of current interest.
Repeatability (The maximum credit hours a student may have for this course.): 10
Grade Mode: Standard
Instructional Method: Research
Term offered: Fall, Spring
Fall - Instructor of Record: Max Fletcher
Spring - Instructor of Record: Joseph C Callaway
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ANAT 841 - Behavioral Neuroscience
Cr Hrs: 3 (48-0-0)
GR
This elective is designed to introduce graduate students to behavioral approaches to the study of neuroscience. This course combines lectures with review of both classic and current literature in order to develop an extensive appreciation of behavioral techniques used to study neuroscience questions.
Instructional Method: Lecture
Term offered: Fall
Fall - Instructor of Record: John D Boughter, Jr
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ANAT 927 - Special Topics in Neurobiology
Cr Hrs: 1-5
GR
Seminars, lectures, and a laboratory experience in one or more specialized fields in the anatomical sciences, including but not limited to many aspects of neuroscience and cell biology.
Repeatability (The maximum credit hours a student may have for this course.): 20
Grade Mode: Standard
Instructional Method: Lab, Seminar
Prerequisites: Permission of instructor
Term offered: Fall, spring
Fall - Instructor of Record: Max Fletcher
Biostatistics and Epidemiology
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BIOE 720 - Biostatistics for Public Health
Cr Hrs: 3 (48-0-0)
GR
This course provides an introduction to the use of statistical techniques in biomedical and public health research. The course will cover common descriptive statistics including the mean, median, and standard deviation as well as techniques for testing hypotheses (analysis of variance, t-tests, regression, nonparametric methods) and issues in sampling and design of experiments. The class will be taught using online methods.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lecture
Term offered: Fall
Fall - Instructor of Record: Chi-Yang Chiu
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BIOE 727 - Principles of Epidemiology
Cr Hrs: 3 (48-0-0)
GR
This online course introduces the basic principles and methods of epidemiology and demonstrates their applicability in the fields of public health and clinical research. Topics to be covered include the historical perspective of epidemiology, measures of disease occurrence and association, study design, disease screening, and causal inference. Study design content will cover experimental, cohort and case-control studies as well as challenges in design and analysis including bias, confounding and random error. Students will be expected to participate in discussion boards, complete weekly homework assignments, and take a mid-term and final exam.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lecture
Term offered: Fall
Fall - Instructor of Record: Alex Mason
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BIOE 728 - Health Behavior Intervention
Cr Hrs: 3
GR
This course introduces the theory and methods of interventions for health behaviors, and demonstrates their applicability in the fields of public health and clinical research. Topics to be covered include the applicable theories of health behavior change, the different mechanisms of intervention, empirical validation of intervention methods, the format of intervention methods, and the phases of validation (efficacy, effectiveness, and dissemination). Students will be expected to participate in discussion boards, complete weekly homework assignments, and take a mid-term and final exam.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lecture
Term offered: Spring
Spring - Instructor of Record: Karen Derefinko
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BIOE 729 - Introduction to Health Disparities
Cr Hrs: 3 (48-0-0)
GR
This course will provide an overview of health disparities and the historical underpinnings of health
disparities as well as an examination of the social determinants of health in the United States.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lecture
Term offered: Spring
Spring - Instructor of Record: Shelley White-Means
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BIOE 740 - Ethical and Legal Issues in Clinical Research
Cr Hrs: 3 (48-0-0)
GR
This course will examine ethical and legal principles and issues in clinical research, including attention to topics such as the Nuremberg Code, Belmont Report, federal standards for protection of human subjects, FDA guidelines for drug and device development, good clinical practice standards, and how these guidelines may be applied to the development, conduct, and reporting of clinical research.
Grade Mode: P/F
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lecture
Prerequisites: Be enrolled in the Certificate in Clinical Investigation Program, or by permission of the program director in the Certificate in Clinical Investigation Program
Term offered: Spring (Not currently offered)
Spring - Instructor of Record: Mark A Miller
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BIOE 750 - Fundamentals of Clinical Investigation
Cr Hrs: 3 (48-0-0)
GR
This course will present an introduction to the different types of clinical research and practical methods that investigators can use in the conduct of multidisciplinary clinical research. Observational cohort studies, case-control studies, and Phase I-IV intervention-based randomized controlled clinical trials will be presented. Design distinctions, sampling and randomization procedures, data integrity, data-analysis concerns, and practical conduct for these investigative approaches will be examined. This course will also review ethical issues in conducting research in people, federal guidance for the conduct of clinical research, and the dynamic influence of behavior on the conduct of clinical research particularly in regards to recruitment, retention, and adherence in clinical trials.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lecture
Term offered: Spring
Spring - Instructor of Record: Mathilda C Coday
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BIOE 800 - Master’s Thesis and Research
Cr Hrs: 1-9
GR
Research performed under the direction and supervision of the respective student’s Research Advisor, in partial fulfillment of the requirements for the degree of Master of Science.
Repeatability (The maximum credit hours a student may have for this course.): 12
Grade Mode: P/NP
Instructional Method: Research
Prerequisites: Special permission required (Permission of instructor)
Term offered: Fall, Spring
Fall - Instructor of Record: Simonne S Nouer
Spring - Instructor of Record: Simonne S Nouer
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BIOE 804 - Master’s Project
Cr Hrs: 1-6
GR
Students will work on their master’s project in conjunction with advisor and master’s committee. Research-based course. Credit variable (1-6) Is assigned by instructor.
Repeatability (The maximum credit hours a student may have for this course.): 24
Grade Mode: P/NP
Instructional Method: Research
Term offered: Fall, Spring
Fall - Instructor of Record: Simonne S Nouer
Spring - Instructor of Record: Simonne S Nouer
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BIOE 805 - Using R for Biostatistics I
Cr Hrs: 2 (32-0-0)
GR
The course will introduce students to R, a versatile open-source language and programming environment. R is widely used for data analysis and visualization by statisticians and data scientists. This course will introduce students to the basics of R language, Students should have a thorough understanding of the basic statistics covered in BIOE811 and BIOE821 (Biostatistics for the Health Sciences I and II).
Grade Mode: Standard
Instructional Method: Lecture
Term offered: Fall
Fall - Instructor of Record: Hyo Young Choi
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BIOE 806 - Using R for Biostatistics II
Cr Hrs: 2 (32-0-0)
GR
This is a second course in R, a versatile open-source language and programming environment. R is widely used for data analysis and visualization by statisticians and data scientists. This course will delve into the details of R programming focussing on the powerful model formula syntax for specifying statistical models, implementing generalized linear models, and data wrangling. Students should
be familiar with R at the level of BIOE805 (R for Biostatistics I).
Grade Mode: Standard
Instructional Method: Lecture
Term offered: Spring
Spring - Instructor of Record: Saunak Sen
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BIOE 810 - Independent Study
Cr Hrs: 1-3
GR
An in-depth study of some aspect of epidemiology in which the student has special interest. Study is done independently with Faculty approval and supervision.
Repeatability (The maximum credit hours a student may have for this course.): 12
Grade Mode: Standard, P/F
Instructional Method: Independent Study
Prerequisites: Special permission required (Permission of instructor)
Term offered: Fall, Spring
Fall - Instructor of Record: Simonne S Nouer
Spring - Instructor of Record: Simonne S Nouer
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BIOE 811 - Biostatistics for the Health Sciences I
Cr Hrs: 4 (48-16-0)
GR
This course provides students with an introduction to descriptive statistics, probability and probability distributions, estimation, and one and two sample hypothesis testing, including paired and unpaired situations, for normally distributed and ordinal data. Students will also be introduced to one-way analysis of variance, including multisample inference, one-way ANOVA, fixed-effect and random effects models, and intraclass correlation coefficients. This course also includes a mandatory statistical computing laboratory that uses SAS for data analysis throughout the semester.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lecture, Lab
Term offered: Fall
Fall - Instructor of Record: Elizabeth A Tolley
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BIOE 812 - Fundamentals of Epidemiology
Cr Hrs: 3 (48-0-0)
GR
The course introduces the basic principles and methods of epidemiology and demonstrates their applicability in the field of public health. Topics to be covered include the historical perspective of epidemiology, measures of disease occurrence and of association, clinical epidemiology, disease screening, causal inference, and study design.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lecture
Term offered: Fall
Fall - Instructor of Record: Simonne S Nouer
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BIOE 813 - Fundamentals of SAS for Epidemiology
Cr Hrs: 3 (32-32-0)
GR
This course provides the foundation computing skills for independent analysis of epidemiologic data. Topics to be covered include an introduction to SAS as a research tool; Operating with SAS for Windows environment; Reading internal and external data into SAS; Working with variables and SAS functions; Using logical statements; Introducing SAS procedures - especially those that produce descriptive statistics; Performing simple inferential tests and power analysis; combining datasets; Reshaping data; and Introducing macro language. This course consists of 2 hour lecture and 1 hour laboratory session per week.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lecture, Lab
Term offered: Fall
Fall - Instructor of Record: Jim Y Wan
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BIOE 821 - Biostatistics for the Health Sciences II
Cr Hrs: 4 (64-0-0)
GR
This course provides students with a continuation of the knowledge gained in BIOE 811. The second semester covers analysis of variance for commonly used experimental designs, regression analysis, and analysis of categorical data. Methods of analysis and hypothesis testing for three or more treatments are presented for various experimental designs and treatment combinations for normally distributed and ordinal data. Methods of simple and multiple linear regression analysis are presented for observational and experimental data. One- and two-sample estimation and hypothesis testing methods for categorical data are covered for observational and experimental data. This course includes a mandatory statistical computing laboratory that uses SAS for data analysis throughout the semester.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lecture
Prerequisites: BIOE 811 Biostatistics for the Health Sciences I
Term offered: Spring
Spring - Instructor of Record: Elizabeth A Tolley
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BIOE 822 - Advanced Epidemiology
Cr Hrs: 4 (64-0-0)
GR
This course provides the foundation skills for independent analysis of epidemiological data. Topics to be covered include the analysis of vital statistics data, statistical analysis of simple epidemiological measures, identification and control of confounders in epidemiological data, logistic regression, and proportional hazards modeling. At the end of the semester, students will be able to analyze data from matched and unmatched case-control studies, case cohort studies, and traditional cohort designs. The course includes a mandatory statistical computing laboratory.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lecture
Prerequisites: BIOE 811 Biostatistics for the Health Sciences I, BIOE 812 Fundamentals of Epidemiology
Term offered: Spring
Spring - Instructor of Record: Simonne S Nouer
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BIOE 823 - Randomized Clinical Trials
Cr Hrs: 3 (48-0-0)
GR
This course will allow the student to understand and analyze the many critical facets of the most precise design for clinical studies in humans: randomized clinical trials. Using a case-based approach, students will learn the importance of precise hypothesis description, selection of an at risk cohort for study, and the power of randomization in helping balance the study groups on a number of known and unknown confounding factors. Important issues with regard to subject recruitment, patient management, and data quality control will be emphasized. Students will learn to perform their own sample size calculations and use actual statistical packages to outline real clinical trial results data.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Hybrid
Instructional Method: Lecture
Prerequisites: BIOE 811 Biostatistics for the Health Sciences I ; BIOE 812 Fundamentals of Epidemiology
Term offered: Fall
Fall - Instructor of Record: Mathilda C Coday
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BIOE 824 - Genetic Epidemiology: Methods and Applications
Cr Hrs: 3 (48-0-0)
GR
This course will provide an overview of the rapidly advancing field of genetic epidemiology and genomics. It is designed for a broad audience and targets students, fellows, and residents with diverse background in the health sciences. The course will start with an introduction to molecular genetics, genome organization, and principles of inheritance and quantitative genetics. This will be followed by a series of lectures and discussions on human genome diversity, linkage mapping, genome-wide association studies (GWAS), QTLs, and the technological advances driving genome research. Topics covered include epigenetics and gene expression, personalized genomics, and ethical implications. The course will involve a combination of lectures, independent study/learning, discussion sessions, and some hands-on computer work.
Grade Mode: Standard
Instructional Method: Lecture
Term offered: Spring
Spring - Instructor of Record: Khyobeni Mozhui
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BIOE 834 - Epidemiology of Childhood Diseases
Cr Hrs: 2 (32-0-0)
GR
This seminar will provide an overview of the epidemiology of selected conditions and diseases affecting children as well as demonstrate the childhood origins of some adult chronic disease. For most of these conditions, information about the pattern of occurrence, data about risk factors and effectiveness of various preventive or therapeutic interventions will be discussed. Public use sources of information such as the National Health and Examination Survey (NHANES), National Ambulatory Medical Care Survey (NAMCS), CDC “Pink Book”, Child and Adolescent Health Measurement Initiative (CAHMI) and Youth Risk Behavior Surveillance System (YRBSS) will be introduced and discussed. Additionally, some of the unique and challenging aspects of research in pediatric epidemiology such as issues of childhood growth and development, maternal (intrauterine) origins of disease and parental role in disease diagnosis and treatment will be introduced. In the last weeks of course students will be asked to synthesize the information presented in the course by identifying, presenting and evaluating the available epidemiological information on a childhood disease or condition of their choice.
Grade Mode: P/F
Mode of Delivery (Online or Hybrid): Hybrid
Instructional Method: Lecture
Prerequisites: BIOE 812 Fundamentals of Epidemiology
Term offered: Spring
Spring - Instructor of Record: Marion Elizabeth Hare
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BIOE 845 - Biostatistics for Integrated Biomedical Sciences
Cr Hrs: 2 (32-0-0)
GR
Unit 1: Descriptive statistics and looking at data
Unit 2: Review of study designs; measures of disease risk and association
Unit 3: Probability, Bayes’ Rule, Diagnostic Testing
Unit 4: Probability distributions
Unit 5: Statistical inference (confidence intervals and hypothesis testing)
Unit 6: P-value pitfalls; types I and type II error; statistical power; overview of statistical tests
Unit 7: Tests for comparing groups (unadjusted); introduction to survival analysis
Unit 8: Regression analysis; linear correlation and regression
Unit 9: Logistic regression and Cox regression
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lecture
Prerequisites: Special permission required (All non-Biomedical Sciences students require permission of instructor)
Term offered: Spring (Not currently offered)
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BIOE 847 - Advanced SAS Programming
Cr Hrs: 2 (16-32-0)
GR
This course provides advanced programming techniques in SAS/SQL, MACRO languages, and SAS Graphics. The natural flow of the course is intended to start with an introduction to simple SQL programming using a single dataset followed by discussions on how to work with multiple datasets with common primary key variables. Upon completing the SQL component, a smooth transition is planned to simple MACRO programming in SAS, which will be gradually advanced to more efficient yet complicated MACRO programming. This class is taught in a hybrid setting where we will have onsite review lectures in the SAS-laboratory in the Department of Preventive Medicine, and the students will be required to have a laptop with SAS access where they will work on hands-on practice of exercises from SAS SQL and MACRO Programing as well as SAS Graphics.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Hybrid
Instructional Method: Lecture, Lab
Prerequisites: BIOE 813 Fundamentals of SAS for Epidemiology
Term offered: Spring
Spring - Instructor of Record: Mehmet Kocak
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BIOE 848 - Professional Experience and Prior Learning Assessment
Cr Hrs: 1-3
GR
This course recognizes that work experience can provide valuable learning experiences that can complement learning acquired through formal education. This course offers an assessment of experiential learning, performed through the construction of a portfolio, that emphasizes the connection between learning from work experience, practice skills, continuing education, clinical investigatory knowledge, and its translational application to research. This portfolio must be submitted the semester prior to course registration for committee review and credit-hour assignment. This course cannot be repeated.
Grade Mode: P/F
Instructional Method: Clinical
Prerequisites: Special Permission Required (Permission of instructor)
Term offered: Fall, Spring
Fall - Instructor of Record: Simonne S Nouer
Spring - Instructor of Record: Simonne S Nouer
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BIOE 850 - Categorical Data Analysis
Cr Hrs: 2 (32-0-0)
GR
This course begins by an introduction and review of most common discrete random variables and their probability distributions, followed by a brief discussion of ‘parameter estimation’ as a general concept in Theoretical Statistics. Then, we introduce the concept of inferential statistics by discussing one sample confidence interval and hypothesis testing for one- and two-sample designs, which includes the definition of and testing for statistical independence through the most commonly used chi-squarebased tests for 2x2, Rx2, 2xC, and RxC contingency tables and sets of (stratified) contingency tables. Then, the generalized linear model is introduced as the backbone for model building that focuses on the estimation of effects of one or more predictors on a binary response variable or on a count variable, including model inference and model diagnostics checking. Specific topics for the modeling of categorical data include logistic regression for dichotomous and polytomous response, conditional logistic regression, generalized estimating equations, and generalized linear mixed modeling for models with random effects. In addition, the course will explore log-linear modeling for count data. The relation of the various approaches and procedures using SAS will be demonstrated. The course focuses on application of the above approaches to observational and clinical trial designs.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Hybrid
Instructional Method: Lecture
Prerequisites: BIOE 812 Fundamentals of Epidemiology and BIOE 821 Biostatistcs for Health Sci II
Term offered: Fall
Fall - Instructor of Record: Mehmet Kocak
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BIOE 852 - Introduction to Biostatistics for the Health Sciences
Cr Hrs: 3 (48-0-0)
GR
This introductory course provides a basic foundation for further coursework in biostatistics. It is provides students with a step-by-step, hands-on approach to using data for statistical analysis. This course emphasizes how to ask appropriate research questions and interpret statistical results. Statistical methodology includes a thorough introduction to the meaning of relevant terms, assumptions, statistical computations, and appropriate interpretation of results. Students must be able to read and understand algebraic equations.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lecture
Term offered: Fall
Fall - Instructor of Record: Xueyuan Cao
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BIOE 864 - Data Science 2: Statistical Methods for Observational Studies
Cr Hrs: 1 (16-0-0)
GR
This second course in data science Data Science 2: Statistical Methods for Observational Studies focuses on statistical approaches in data science, especially those relating to observational studies. This course can also be chosen independently for those students that wish to learn about observational studies in general. Students will learn about the distinction of causal analysis vs. association studies and the consequences for appropriately choosing statistical methods for data analysis. Sources of bias in observational studies and statistical methods to tackle these are discussed. This 1 credit course is taught with hands-on exercises and the student is expected to be comfortable with algorithmic approaches and computer programming.
Grade Mode: Standard
Instructional Method: Lecture
Prerequisites: BIOE 811 , BIOE 821 , BIOE 805 Using R for Biostatistics I (or equivalent)
Term offered: Fall
Fall - Instructor of Record: Fridtjof Thomas
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BIOE 865 - Linear Regression Methods for the Health Sciences
Cr Hrs: 2 (32-0-0)
GR
In this course, students will learn how multiple linear regression models are derived, use software to implement them, learn what assumptions underlie the models, learn how to test whether data meet those assumptions and what can be done when those assumptions are not met, and develop strategies for building and understanding useful models.
Grade Mode: P/NP
Mode of Delivery (Online or Hybrid): Hybrid
Instructional Method: Lecture
Prerequisites: BIOE 811 - Biostatistics for the Health Sciences I and BIOE 821 - Biostatistics for the Health Sciences II or equivalent
Term offered: Fall
Fall - Instructor of Record: Elizabeth Tolley
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BIOE 866 - Linear Mixed Models
Cr Hrs: 2 (32-0-0)
GR
This course provides the advanced skills necessary for independent statistical analysis of epidemiologic and clinical data containing clustered observations and random effects. Topics to be covered include unrestricted and restricted maximum likelihood estimation, Akaike’s information criterion, standard general linear models, linear random effects models, linear covariance pattern models, and linear random coefficient models. The course focuses on applications requiring flexible modeling of variance and covariance structures for clustered data when observations from a common cluster are correlated. The approaches covered in the course are particularly relevant for analysis of hierarchical and longitudinal data having Gaussian distributed error.
Grade Mode: Standard
Instructional Method: Lecture
Prerequisites: BIOE 821 , BIOE 822
Term offered: Fall
Fall - Instructor of Record: Tamekia Jones
Fall - Additional Instructor 1: Jim Wan
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BIOE 867 - Data Science 1:Using Electronic Medical Record Data for Clinical Research
Cr Hrs: 2 (32-0-0)
GR
This first course in data science Data Science 1: Using Electronic Medical Record Data for Clinical Research is an opportunity to gain ‘hands-on’ experience analyzing data to answer specific research questions. Methods and theoretical issues introduced in earlier courses will be covered, but with a focus on practical analysis issues with actual data. Students work in small groups (2-3) on separate research topics, with each group using a different dataset that we provide. Data will come from CERNER Health Facts, the UTHSC Enterprise Data Warehouse and other data sources. This 2 credit course is taught with hands-on exercises and the student is expected to be comfortable with computer programming.
Grade Mode: Standard
Instructional Method: Lecture
Prerequisites: BIOE 811 Biostatistics for the Health Sciences I; BIOE 821 Biostatistics for the Health Sciences II; BIOE 805 Using R for Biostatistics I (or equivalent); or Consent of instructor
Term offered: Not currently offered
Fall - Instructor of Record: Robert Davis
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BIOE 868 - Survival Analysis
Cr Hrs: 2 (32-0-0)
GR
Survival analysis refers to the statistical approach to analyze the occurrence and timing of events. Students will gain familiarity with the characteristics of time-to-event data such as the presence of censoring and time-varying covariates, and will learn to master the necessary statistical techniques to design and analyze studies with survival data, including the construction and interpretation of Kaplan-Meier estimates and the Cox proportional hazards model. This course also extends the standard Cox model by introducing time-varying covariates and stratification as a way of dealing with non-proportionality of hazards. The course utilizes the software SAS and especially PROC LIFETEST and PROC PHREG. This 2 credit course is taught with hands-on exercises and the student is expected to bring his/her own computer with a fully functional SAS installation.
Grade Mode: Standard
Instructional Method: Lecture
Prerequisites: BIOE 811 - Biostatistics for the Health Sciences I , BIOE 813 - Fundamentals of SAS for Epidemiology ,BIOE 821 - Biostatistics for the Health Sciences II
Term offered: Spring
Spring - Instructor of Record: Fridtjof Thomas
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BIOE 869 - Data Science 3
Cr Hrs: 2 (32-0-0)
GR
The seminar-based course will cover advanced topics in data science reflecting the interest of participating students and faculty. The seminars are designed to cover a wide variety of methodological topics in data science from a statistical and informatics perspective.
Grade Mode: Standard
Instructional Method: Seminar
Term offered: Not currently offered
Spring - Instructor of Record: Saunak Sen
Biomedical Engineering
Comparative Medicine
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CMED 711 - Essentials of Animal Experimentation
Cr Hrs: 2 (16-32-0)
GR
This course is designed to provide an overview of appropriate and effective use of animals in biomedical research. Topics to be covered include regulatory requirements, biomethodology, principles of experimental animal surgery, postoperative veterinary care, and animal care and use procedures. Emphasis is placed on practical experience with living animals and practice of techniques under anesthesia. No text is required.
Grade Mode: Standard
Instructional Method: Lecture, Lab
Location offered: Coleman Building. Lecture: Room B138/140. Lab: Room B103/E213
Term offered: Fall
Fall - Instructor of Record: David J Hamilton
Fall - Additional Instructor 1: Elizabeth A Tolley
Fall - Additional Instructor 2: Brianne Hibl
Fall - Additional Instructor 3: Tyler Aycock
Fall - Additional Instructor 4: Jeffery D Steketee
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CMED 712 - Biology and Pathophysiology of Laboratory Animals I
Cr Hrs: 2 (32-0-0)
GR
This course expands on much of the material covered in CMED 711 Emphasis will be placed on the following species: mice, rats, guinea pigs, rabbits, hamsters, and other rodents. Subjects to be covered include the taxonomy, applied anatomy and physiology, pharmacology, genetics, immunology, nutrition, behavior, husbandry, use as an animal model, and in-depth pathophysiology of significant diseases of each species Emphasis will be placed on features that make a particular species uniquely suitable for certain types of research.
Grade Mode: Standard
Instructional Method: Lecture
Prerequisites: CMED 711 Essentials of Animal Experimentation
Term offered: Spring
Spring - Instructor of Record: David J Hamilton
Spring - Additional Instructor 1: Amy J Funk
Spring - Additional Instructor 2: Brianne M Hibl
Spring - Additional Instructor 3: Jerold E Rehg
Spring - Additional Instructor 4: S. Tyler Aycock
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CMED 713 - Biology and Pathophysiology of Laboratory Animals II
Cr Hrs: 2 (32-0-0)
GR
Continuation of CMED 712. Emphasis will be placed on the following species: dogs, cats, sheep, goats, pigs and a variety of nonhuman primates. Rarely used research species, such as amphibians, reptiles, fish, avian species, and certain invertebrates will be covered to a lesser degree. Subjects to be covered include the taxonomy, applied anatomy and physiology, pharmacology, genetics, immunology, nutrition, behavior, husbandry, use as an animal model, and in-depth pathophysiology of significant diseases of each species. Emphasis will be placed on features that make a particular species uniquely suitable for certain types of research.
Grade Mode: Standard
Instructional Method: Lecture
Term offered: Spring
Spring - Instructor of Record: David J Hamilton
Spring - Additional Instructor 1: Tyler Aycock
Spring - Additional Instructor 2: Amy J Funk
Spring - Additional Instructor 3: Tiffani S Rogers
Spring - Additional Instructor 4: Jerold E Rehg
Forensic Dentistry
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PFOR 800 - MDS (Forensic Dentistry) Research & Manuscript
Cr Hrs: 1-6
GR
This course provides postgraduate students with the experience of engaging in dental and related sciences, and to pursue a Masters of Dental Science (MDS) degree in the UTHSC College of Graduate Health Sciences. In this course, students will work on individual research projects under the supervision of an individual advisor experienced in research methodologies and scientific writing. Students will work on the inception, implementation, and submission for publication of a research project with an individual advisor. Student activities include library research, writing a literature review, developing a research protocol, hands-on research, gathering and analyzing data, interpreting experimental results, developing conclusions, and publishing outcomes. Submission for publication of the original research is required.
Grade Mode: P/F
Instructional Method: Lecture
Term offered: Fall/Spring
Fall - Instructor of Record: Murray K. Marks
Spring - Instructor of Record: Murray K. Marks
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PFOR 801 - Forensic Science Journal Club
Cr Hrs: 1 (16-0-0)
GR
An evaluation and discussion of relevant historical and current methodology and trends in forensic dentistry and forensic science (focus choice of faculty).
Repeatability (The maximum credit hours a student may have for this course.): may be repeated 3 times for a maximum of 3 credits
Grade Mode: Standard
Instructional Method: Lecture
Term offered: Fall
Fall - Instructor of Record: Murray K. Marks
Fall - Additional Instructor 1: James M. Lewis
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PFOR 802 - Introduction to Forensic Science
Cr Hrs: 2 (32-0-0)
A survey of the American Academy of Forensic Science forensic specialties and provides basic information on morgue protocols. This course provides the basic medico-legal knowledge and understanding of morgue protocols necessary to perform duties in a medical examiner’s office.
Grade Mode: Standard
Instructional Method: Lecture
Term offered: Fall
Fall - Instructor of Record: Murray K. Marks
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PFOR 803 - Radiology
Cr Hrs: 2 (32-0-0)
This course offers the fundamentals of theory and practice that constitute a working knowledge of the radiologic sciences as they apply to general and forensic dentistry. Laboratory exercises will be utilized to develop practical skills in the area of dental radiographic procedures which serve as the foundation for intraoral radiographic image acquisition and interpretation. The course will cover basic principles and anatomy revealed by intraoral and panoramic imaging as well as cone beam computed tomography (CBCT).
Grade Mode: Standard
Instructional Method: Didactic
Term offered: Fall
Fall - Instructor of Record: Jeffrey W. Peeke
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PFOR 804 - Forensic Odontology I
Cr Hrs: 3 (48-0-0)
This course is a historical and practical demonstration of the theory and practice in human forensic identification procedures and age assessment methodology. Its aim is to prepare the student to perform human identifications and age assessments in a medical examiner office setting as well as in mass disaster situations. It provides the basic medico-legal knowledge necessary to perform these duties in its application to law and the U.S. legal system.
Grade Mode: Standard
Term offered: Spring
Spring - Instructor of Record: James M. Lewis
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PFOR 805 - Forensic Science II
Cr Hrs: 3 (48-0-0)
GR
An advanced exposure to specific forensic science protocols including autopsy and report findings, crime scene procedures including clandestine grave excavation, legal proceedings of criminal investigations, crime scene rules, corporeal evidence, expert testimony, and courtroom dynamics.
Grade Mode: Standard
Instructional Method: Didactic
Term offered: Fall
Fall - Instructor of Record: Murray K. Marks
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PFOR 806 - Forensic Odontology II
Cr Hrs: 3 (48-0-0)
GR
A continuation of Forensic Odontology I with emphasis on the role of the forensic dentist in pattern injury recognition, analysis and comparison; human abuse; civil litigation; court room dynamics and their role as an expert witness. It provides the basic medico-legal knowledge necessary to perform these duties in its application to law and the U.S. legal system.
Grade Mode: Standard
Instructional Method: Didactic
Term offered: Fall
Fall - Instructor of Record: James M. Lewis
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PFOR 807 - Dental Specialties
Cr Hrs: 2 (32-0-0)
GR
This course is a review of the current dental school level standards and trends in the areas of biomaterials, endodontics, pedodontics, periodontics, prosthodontics, orthodontics, oral/maxillofacial surgery, and oral medicine. It provides basic knowledge in recognition of dental materials, restorations, prostheses, and oral pathology in order to assist the forensic dentist perform duties in application to the law and medico-legal system.
Grade Mode: Standard
Instructional Method: Didactic
Term offered: Fall
Fall - Instructor of Record: O. Lee Wilson
Genetics, Genomics, and Informatics
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GGI 820 - Genetics, Genomics, and Informatics Seminar
Cr Hrs: 1 (16-0-0)
GR
This is the departmental seminar series for faculty postdoctoral scholars and faculty. Weekly presentations will be made by visiting scholars, GGI faculty and postdocs.
Grade Mode: P/NP
Instructional Method: Seminar
Term offered: Fall, Spring
Fall - Instructor of Record: Megan Mulligan
Spring - Instructor of Record: Athena Davenport, Byron C. Jones
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GGI 828 - Foundations of Artificial Intelligence in Healthcare I
Cr Hrs: 3 (48-0-0)
GR
This course introduces the basic machine learning paradigms. Students will participate in a two hour journal club-style discussion of historical and topical literature on a particular learning paradigm every other week. The following week, a seminar on current research in the previous week’s topic will be presented. Mid-term, in consultation with the instructor, the students will identify a biomedical/healthcare area of interest that may benefit from the application of AI/ML. The course culminates with the students submitting a literature review on that outlines the deficits in the knowledge on the topic that could addressed by AI/ML.
Grade Mode: Pass/Fail
Mode of Delivery (Online or Hybrid): Hybrid
Instructional Method: Lecture/Seminar
Term offered: Fall
Fall - Instructor of Record: Robert L. Davis
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GGI 829 - Foundations of Artificial Intelligence in Healthcare II
Cr Hrs: 3 (48-0-0)
GR
This is a continuation of Foundations of Artificial Intelligence in Healthcare I. In the same format (two hour journal club-style discussion of historical and current literature followed the next week by a seminar on current research), students will explore feature engineering and feature selection, model fitting, performance metrics, and basic principles of model project design. The course will culminate with student design projects addressing the deficits identified in their project from Foundations of Artificial Intelligence in Healthcare I.
Grade Mode: Pass/Fail
Mode of Delivery (Online or Hybrid): Hybrid
Instructional Method: Lecture/Seminar
Term offered: Fall
Fall - Instructor of Record: Robert L. Davis
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GGI 840 - Special Topics in Genetics, Genomics, and Informatics
Cr Hrs: 3 (48-0-0)
GR
Repeatability (The maximum credit hours a student may have for this course.): 6
Grade Mode: P/NP
Instructional Method: Lecture
Term offered: Fall
Fall - Instructor of Record: Byron C. Jones
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GGI 901 - Integrative Genetics
Cr Hrs: 3 (48-0-0)
GR
This is a proseminar course to provide basic knowledge of classical, quantitative and modern molecular genetics. We expect that not all of the students entering the GGI graduate program will be equally versed in the various sub-disciplines, so this course can be considered to be “leveling.”
Grade Mode: P/NP
Instructional Method: Lecture
Term offered: Fall
Fall - Instructor of Record: Athena Davenport
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GGI 902 - Advanced Pharmacogenomics
Cr Hrs: 3 (48-0-0)
GR
This is a course designed for the Genetics, Genomics, and Informatics track in the Integrative Biosciences Ph.D program. The course is offered collaboratively between the Departments of Genetics, Genomics, and Informatics in the College of Medicine and Pharmaceutical Sciences in the College of Pharmacy. Lectures on clinical aspects will be presented by the College of Pharmacy faculty during their regularly offered PHSC 222 course and preclinical/basic science aspects will be presented by College of Medicine Faculty. Topics covered will include basic pharmacokinetics and pharmodymics, genetics of drug metabolizing enzymes, genetics of drug receptors, individual differences in targeted and nontargeted drug responses, cardiovascular, central nervous system and infectious disease pharmacology, and genetics of cancer treatment. The course content also includes ethical/legal and regulatory topics.
Grade Mode: Standard
Instructional Method: Lecture
Term offered: Fall
Fall - Instructor of Record: Byron Jones
Spring - Instructor of Record: Byron Jones
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GGI 903 - Medical Genetics
Cr Hrs: 3 (48-0-0)
GR
This course will provide a foundation in medical genetics and aims to equip students with a better understanding of the relationship between basic genetics and clinical medicine. The course presents an overview of the disease process and differential diagnosis of related genetic disorders and includes the following topics: birth defects/embryology, prenatal diagnosis, inborn errors of metabolism, common diseases, monogenic, polygenic, and multifactorial genetics, genetic screening, immunogenetics, cancer genetics, pharmacogenetics, hemoglobinopathies, ciliopathies, genetic counselling and the ethical, legal and social issues that arise in medical genetics.
Grade Mode: Standard
Instructional Method: Lecture
Term offered: Fall
Fall - Instructor of Record: Claire L Simpson
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GGI 905 - Bioinformatics Summit
Cr Hrs: 1 (16-0-0)
GR
Each year, UTHSC, U of Memphis and the University of Kentucky sponsor a 2-1/2 day program in bioinformatics in retreat off campus. All GGI Ph.D. students will be required to attend each year for their first two years and highly encouraged and supported each year thereafter. Organizers of the summit invite speakers in key and emerging areas of genetics, genomics and bioinformatics. Following the summit, the GGI Department will hold a debriefing and each student attending for credit will be required to present a seminar paper on two topics discussed.
Grade Mode: P/NP
Instructional Method: Seminar
Term offered: Spring
Spring - Instructor of Record: Byron Jones
Graduate Dental Science
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PDSC 820 - Research Methods
Cr Hrs: 1 (8-16-0)
GR
The course is composed of two sections. The biostatistics portion of this course introduces students to widely used methods for analysis of experimental and observational data with orientation toward statistical inference from dental research. The experimental design aspect of this course serves as an introduction to research, including methods for handling experimental data.
Grade Mode: P/NP
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Other
Location offered: Memphis/Knoxville
Prerequisites: Acceptance into a postgraduate dental program
Term offered: Fall
Fall - Instructor of Record: Mark Scarbecz (Memphis); Murray Marks (Knoxville)
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PDSC 821 - Dental Ethics
Cr Hrs: 1 (0-32-0)
GR
Courses Online Dental Ethics (CODE) is a series of online courses in dental ethics and professionalism. The American College of Dentists developed and manages CODE and related resources at www.dentalethics.org. There are no registration fees or tuition and the American College of Dentists welcomes and encourages coordinated educational experiences in educational facilities. There are currently over 30 online ethics modules intended for all dental students and professionals. Sixteen of the modules identified as particularly relevant to postgraduate dental education and the specialty practice of dentistry will constitute this course.
Grade Mode: P/NP
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Lab
Prerequisites: Acceptance into a postgraduate dental program
Term offered: Fall, Spring
Fall - Instructor of Record: David Richard Cagna
Spring - Instructor of Record: James Lewis
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PDSC 822 - Oral Sciences I
Cr Hrs: 1 (16-0-0)
GR
This course is designed to provide fundamental knowledge on the development, morphology, histology, neuroanatomy, circulation, and function of basic tissue, and dentofacial structures including the salivary glands, teeth, and the temporomandibular joint. The understanding of this science is essential: it lays the foundation for evidenced-based insight into the form and structure of the orofacial complex. This is a mainly seminar-based and discussion-based course wih some didactic lectures. Topic handouts are provided electronically for guidance. Reference to the highly recommended reading list is encouraged and advised. Attendance is required per College of Dentistry Policy. Mid-term and final examination are mandatory.
Grade Mode: Standard
Mode of Delivery (Online or Hybrid): Online
Instructional Method: Online
Prerequisites: Acceptance into a postgraduate dental program
Term offered: Fall
Fall - Instructor of Record: Shokoufeh Shahrabi Farahani
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PDSC 823 - Oral Sciences II
Cr Hrs: 1 (22.5-0-0)
GR
This course is conducted by experts in the areas of biochemistry, microbiology, virology, inflammation and immunology, cell biology, pediatric dentistry, and oral biology. Included are lectures on classification, structure, and function of major periodontopathic bacteria, and virulence factors and pathogenesis of oral microbial diseases. Other microbiology topics include bacterial etiology of dental caries and the role of fluoride therapy, fungal diseases, herpes viruses, hepatitis, and HIV. Host defense topics include inflammation, basic principles of immunology, immunologic mechanisms and cytokines in periodontitis and pulpitis, and the clinical significance of immunologic and other research techniques. Lectures in oral biology address the extracellular matrix and its role in maintenance of tissue function in health and oral diseases; wound healing and repair; bone and cartilage; TMJ pathology; stem cells, mesenchymal stem cell therapy, and oral tissue engineering; mechanisms of oral infection/ cariology; saliva and its role in oral health maintenance; pulp biology and pathology; pain management in dental practice; and oral cancer/tumor markers. Additionally, information on the expanded knowledge of physiologic and biochemical principles involved in oral function are covered. Topics are selected to develop an appreciation of the oral cavity and its associated structures as an integral part of a larger functional unit.
Grade Mode: P/NP
Instructional Method: Lecture, Seminar
Prerequisites: Acceptance into a postgraduate dental program
Term offered: Spring
Spring - Instructor of Record: Mustafa K Dabbous
Spring - Additional Instructor 1: Edwin L Thomas
Spring - Additional Instructor 2: James Patrick Ryan
Spring - Additional Instructor 3: Lorraine Albritton
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PDSC 824 - Biomechanics & Biomaterials
Cr Hrs: 1 (16-0-0)
GR
Metals, polymers, and ceramics are ubiquitous throughout the various dental disciplines. Providing a high quality of oral healthcare requires basic understanding of the physical response of these materials. To stay informed and exploit contemporary and emerging insights, dental professionals must stay current with the biomaterials literature. The purpose of this course is to gain experience in the critical reading and evaluation of the biomaterials literature. Students will learn basic biomechanical and biomaterial concepts and research techniques, while practicing critical evaluations of the dental literature using selected publications relevant to dentistry and research methodology. After completion of this course, a student should be able to successfully evaluate scientific investigations of dental materials and translate this knowledge to their clinical training with the ultimate goal of improving patient treatment and care.
Grade Mode: P/NP
Instructional Method: Seminar
Prerequisites: Acceptance into a postgraduate dental program
Term offered: Fall
Fall - Instructor of Record: Antheunis Versluis
Fall - Additional Instructor 1: Daranee Versluis
Fall - Additional Instructor 2: James C Ragain Jr
Fall - Additional Instructor 3: Franklin Garcia-Godoy
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