PHAC 821 - Advanced Pharmaceutics and Drug Stability

Cr Hrs: 3 (48-0-0)

This course is designed to provide graduate students in pharmaceutical sciences with advanced knowledge in pharmaceutics. This includes an in depth understanding of the physical state of pharmaceutical compounds including amorphous and crystalline states. Techniques used by the pharmaceutical industry to enhance the solubility of poorly soluble compounds, enhancing membrane permeability of poorly permeable compounds, and vivid discussion about the factors that influence the physical and chemical stability of pharmaceutical dosage forms such as humidity, oxygen, and light in the liquid and the solid states. A specific section of the course will be dedicated to study the influence of excipients on the stabilization process of small and large molecules (polypeptide and proteins) including the lyophilization process.

Instructional Method: Lecture
Term offered: Fall